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Cells' Fiery Suicide in HIV Provides New Treatment Hope

12/19/2013

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Most T cells are not killed by the HIV virus itself, but by the body’s defense mechanism. Stopping this process could prevent a patient’s progression to AIDS

By Beth Skwarecki


The difference between HIV infection and full-blown AIDS is, in large part, the massive die-off of the immune system’s CD4 T-cells. But researchers have only observed the virus killing a small portion of those cells, leading to a longstanding question: What makes the other cells disappear? New research shows that the body is killing its own cells in a little-known process. What’s more, an existing, safe drug could interrupt that self-destruction, thereby offering a way to treat AIDS.


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